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Prenatal toxicant exposure and ovarian aging and cancer

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This webinar, originally presented on January 27, 2016, is part of an ongoing series of educational presentations by experts on issues that focus on current and emerging aspects of pediatric and reproductive environmental health.

Learning Objectives:

  • Understand the critical events during ovarian development and their timing.
  • Review the experimental and epidemiological evidence that exposure to environmental toxicants can lead to accelerated ovarian aging and ovarian tumors in adulthood.
  • Understand what is known about mechanisms by which prenatal exposures to toxicants cause ovarian failure and ovarian tumors and understand key data gaps.

Presented By:

Ulrike Luderer, MD, PhD, MPH
University of California, Irvine
Irvine, CA

Dr. Ulrike Luderer is Professor of Medicine in the Division of Occupational and Environmental Medicine and Director of the Environmental Health Sciences Graduate Program at the University of California at Irvine. She also holds joint appointments in the Department of Developmental and Cell Biology and the Program in Public Health at UC Irvine. She earned a Ph.D. in Reproductive Endocrinology and M.D. from Northwestern University, and M.P.H. from the University of Washington, and is board-certified in Internal Medicine and in Occupational and Environmental Medicine.  Dr. Luderer's research focuses on mechanisms of action of reproductive toxicants with a particular emphasis on oxidative stress as a mechanism of ovarian toxicity. Her recent and ongoing work investigates the interactions between genetic deficiencies in antioxidant capacity and toxicant exposure in ovarian toxicity, reproductive aging and ovarian cancer. Dr. Luderer has served on the Scientific Guidance Panel of the California Environmental Contaminant Biomonitoring Program since 2007, including 5 years as Chair. She also currently serves on the California Developmental and Reproductive Toxicant Identification Committee.  She previously served as a member of the Environmental Health Committee of the Science Advisory Board of the US Environmental Protection Agency. She served on the National Toxicology Program/NIEHS Center for the Evaluation of Risks to Human Reproduction Expert Panel on 1- and 2-Bromopropane and chaired the Expert Panel on styrene.

Approximate Completion Time

60 minutes

Continuing Education Information

This course qualifies as continuing education for physicians, nurses, certified health education specialists and other professionals provided by the Centers for Disease Control and its partners. 

Origination Date – 03/01/2016
Expiration Date – 03/01/2018

CE Available

1.0 CME (for physicians)

1.0 CME (attendance for non-physicians)

1.0 CNE (for nurses)

.10 CEU (for other professionals)

1.0 CHES (for certified health education specialists)

Accreditation Statements


This material was supported by the American College of Medical Toxicology (ACMT) and funded (in part) by the cooperative agreement FAIN: U61TS000238 from the Agency for Toxic Substances and Disease Registry (ATSDR).

Acknowledgement: The U.S. Environmental Protection Agency (EPA) supports the PEHSU by providing partial funding to ATSDR under Inter-Agency Agreement number DW-75-92301301. Neither EPA nor ATSDR endorse the purchase of any commercial products or services mentioned in PEHSU publications.

Training Material

  • Presentation
  • Presentation PDF
  • Post-Test
  • How To Obtain Continuing Education Credit